Joseph Reiner


Department Chair
Experimental biophysics, Experimental nanoscience
701 W. Grace, 2111


Ph.D. in Physics, State University of New York Stony Brook, 2003
Dissertation: “Conditional measurements, quantum feedback, and cold atoms in cavity QED”
Advisor: Prof. Luis Orozco, University of Maryland, College Park

M.A. in Physics, State University of New York Stony Brook, 2000

B. S. in Physics, Rochester Institute of Technology, 1997


My research focuses on the development and applications of single molecule measurements.  My lab specializes in biological nanopore sensing in conjunction with optical tweezers and fluorescence microscopy.  Recent efforts have focused on water-soluble nanoclusters, polymer analysis and laser-based heating of the nanopore sensing environment.

Selected Publications

Laser-based temperature control to study the roles of entropy and enthalpy in polymer-nanopore interactions
CE Angevine, JWF Robertson, A Dass, JE Reiner
Science Advances 7 (17), eabf5462, 2021.

Resistive-Pulse Nanopore Sensing of Ligand Exchange at the Single Nanocluster Limit for Peptide Detection
BD Cox, ML Ghimire, MF Bertino, JE Reiner
ACS Applied Nano Materials 3 (8), 7973-7981, 2020.

Ligand-induced structural changes of thiolate-capped gold nanoclusters observed with resistive-pulse nanopore sensing
BD Cox, PH Woodworth, PD Wilkerson, MF Bertino, JE Reiner
Journal of the American Chemical Society 141 (9), 2019, 3792-3796, 2019.

Single molecule nanopore spectrometry for peptide detection
AE Chavis, KT Brady, GA Hatmaker, CE Angevine, N Kothalawala, ...
ACS sensors 2 (9), 1319-1328, 2017.

For a complete summary of Prof. Reiner's professional outputs, you can visit his ORCID Page: or his google scholar profile page:


2017-present: Associate Professor, VCU Department of Physics
2015-present: Associate Director, Nanoscience and Nanotechnology Ph.D. program, VCU
2011-2017: Assistant Professor, VCU Department of Physics.
2005-2011 – Research physicist, National Institute of Standards and Technology, Gaithersburg, MD
2003-2005 – NRC Postdoctoral Fellow, National Institute of Standards and Technology
2000-2003 – Research Assistant, SUNY Stony Brook


American Physical Society (since 1996)


NIST-ARRA Senior Fellowship (2011)
National Research Council/NIST Postdoctoral Research Associateship (2003-2005).